More Than the Sum of Its Parts: Single-Cell Transcriptomics Reveals Epidermal Cell States
Author(s) -
KaWai Mok,
Nivedita Saxena,
Michael Rendl
Publication year - 2018
Publication title -
cell reports
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 6.264
H-Index - 154
eISSN - 2639-1856
pISSN - 2211-1247
DOI - 10.1016/j.celrep.2018.10.041
Subject(s) - epidermis (zoology) , transcriptome , cell , microbiology and biotechnology , biology , human skin , cell type , computational biology , gene expression , genetics , gene , anatomy
Compared to mouse models, less is known about human epidermal cell states and differentiation. In this issue of Cell Reports, Cheng et al. (2018) dissect the cell states and heterogeneity in human epidermis with large-scale transcriptomics of 92,889 single epidermal cells from normal and inflamed skin.
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