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Volume Conduction Coupling of Whisker-Evoked Cortical LFP in the Mouse Olfactory Bulb
Author(s) -
Ana Parabucki,
Ilan Lampl
Publication year - 2017
Publication title -
cell reports
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 6.264
H-Index - 154
eISSN - 2639-1856
pISSN - 2211-1247
DOI - 10.1016/j.celrep.2017.09.094
Subject(s) - olfactory bulb , whisker , neuroscience , coupling (piping) , anatomy , biophysics , olfactory system , biology , chemistry , materials science , central nervous system , metallurgy
Local field potentials (LFPs) are an important measure of brain activity and have been used to address various mechanistic and behavioral questions. We revealed a prominent whisker-evoked LFP signal in the olfactory bulb and investigated its physiology. This signal, dependent on barrel cortex activation and highly correlated with its local activity, represented a pure volume conduction signal that was sourced back to the activity in the ventro-lateral orbitofrontal cortex, located a few millimeters away. Thus, we suggest that special care should be taken when acquiring and interpreting LFP data.

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