Open AccessFeeling Stressed under the Sun? RPA1 Acetylation to the Rescue
Author(s) -
Debabrata Chakravarti,
Tapas K. Hazra
Publication year - 2017
Publication title -
cell reports
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 6.264
H-Index - 154
eISSN - 2639-1856
pISSN - 2211-1247
DOI - 10.1016/j.celrep.2017.08.045
Subject(s) - acetylation , dna damage , replication protein a , dna repair , dna , nucleotide excision repair , microbiology and biotechnology , biology , chemistry , genetics , dna binding protein , gene , transcription factor
Nucleotide excision repair (NER) requires replication protein A (RPA), among others, to respond to DNA damaging agents. In this issue of Cell Reports, He et al. (2017) and Zhao et al. (2017) show acetylation of RPA1 regulates the UV-induced DNA damage response.
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