Open AccessStructural basis for Cas9 off-target activity
Author(s) -
Martin Pacesa,
ChunHan Lin,
Antoine Cléry,
Aakash Saha,
Pablo Arantes,
Katja Bargsten,
Matthew J. Irby,
Frédéric H.T. Allain,
Giulia Palermo,
Peter Cameron,
Paul D. Donohoue,
Martin Jínek
Publication year - 2022
Publication title -
cell
Language(s) - Uncategorized
Resource type - Journals
SCImago Journal Rank - 26.304
H-Index - 776
eISSN - 1097-4172
pISSN - 0092-8674
DOI - 10.1016/j.cell.2022.09.026
Subject(s) - cas9 , biology , crispr , guide rna , heteroduplex , rna , cleave , nuclease , duplex (building) , computational biology , dna , base pair , genome editing , genetics , nucleic acid structure , complementarity (molecular biology) , microbiology and biotechnology , gene
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