My Journey to Open Science

When I was asked by Cell to contribute a story, I decided the most important one is my journey to open science. It begins back in the mid-1980s, when I was a graduate student in Genetics at Harvard University. A good friend, a post-doc named Anil, also loved stories, especially stories about well-known scientists. One was about Tom Maniatis. We’d all heard of him. He’d written what was then considered the bible ofmolecular biology,Molecular Cloning: A LaboratoryManual, a three-volume text we simply called ‘‘Maniatis’’ (Figure 1).