Open AccessHumanizing Transcriptome Engineering
Author(s) -
Prashant Mali
Publication year - 2019
Publication title -
cell
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 26.304
H-Index - 776
eISSN - 1097-4172
pISSN - 0092-8674
DOI - 10.1016/j.cell.2019.06.009
Subject(s) - biology , rna , computational biology , effector , oligonucleotide , transcriptome , crispr , rnase p , guide rna , cas9 , rna silencing , rna interference , microbiology and biotechnology , genetics , dna , gene expression , gene
Transcriptome targeting offers a tunable and reversible approach for cellular engineering. Accordingly, the ability to precisely perturb RNAs has broad implications for research and therapeutics. In this issue, Rauch and colleagues present a new addition to the RNA engineering toolbox that is modular, versatile, and built using human components.
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