Open AccessThe Walrus and the Carpenter: Complex Regulation of Tumor Immunity in Colorectal Cancer
Author(s) -
Grant Dewson,
John Silke
Publication year - 2018
Publication title -
cell
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 26.304
H-Index - 776
eISSN - 1097-4172
pISSN - 0092-8674
DOI - 10.1016/j.cell.2018.06.009
Subject(s) - biology , colorectal cancer , immunity , cancer , cancer research , immune system , immunology , genetics
Immune infiltration has been correlated with survival of patients with colorectal cancer. In this issue, Ziegler et al. reveal complex and unexpected connections between loss of STAT3, mitophagy, and the induction of an adaptive immune response that limits the growth of colorectal carcinoma.
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