Open AccessThe Positives and Negatives of NPR: A Unifying Model for Salicylic Acid Signaling in Plants
Author(s) -
Roger W. Innes
Publication year - 2018
Publication title -
cell
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 26.304
H-Index - 776
eISSN - 1097-4172
pISSN - 0092-8674
DOI - 10.1016/j.cell.2018.05.034
Subject(s) - biology , salicylic acid , false positive paradox , signal transduction , computational biology , bioinformatics , microbiology and biotechnology , biochemistry , computer science , artificial intelligence
Salicylic acid (SA) is a potent inducer of defense gene expression in plants, but how SA activates transcription has been controversial. In this issue of Cell, Ding et al. show that the SA-binding proteins NPR3 and NPR4 function as transcriptional co-repressors, with this activity being blocked by SA.
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