Tubulin Posttranslational Modifications and Emerging Links to Human Disease | Zendy

Maria M. Magiera | Zendy; Puja Singh | Zendy; Sudarshan Gadadhar | Zendy; Carsten Janke | Zendy

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Tubulin Posttranslational Modifications and Emerging Links to Human Disease

Author(s) -

Maria M. Magiera,

Puja Singh,

Sudarshan Gadadhar,

Carsten Janke

Publication year - 2018

Publication title -

cell

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 26.304

H-Index - 776

eISSN - 1097-4172

pISSN - 0092-8674

DOI - 10.1016/j.cell.2018.05.018

Subject(s) - biology , microtubule , tubulin , centrosome , microbiology and biotechnology , cytoskeleton , centriole , microtubule nucleation , microtubule organizing center , mitosis , basal body , flagellum , cell , genetics , cell cycle , gene

Tubulin posttranslational modifications are currently emerging as important regulators of the microtubule cytoskeleton and thus have a strong potential to be implicated in a number of disorders. Here, we review the latest advances in understanding the physiological roles of tubulin modifications and their links to a variety of pathologies.

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