Open AccessPipped at the Post: Pipecolic Acid Derivative Identified as SAR Regulator
Author(s) -
Libo Shan,
Ping He
Publication year - 2018
Publication title -
cell
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 26.304
H-Index - 776
eISSN - 1097-4172
pISSN - 0092-8674
DOI - 10.1016/j.cell.2018.03.045
Subject(s) - pipecolic acid , systemic acquired resistance , biology , monooxygenase , plant immunity , lysine , arabidopsis , regulator , biochemistry , amino acid , enzyme , gene , mutant , cytochrome p450
The non-protein amino acid pipecolic acid (Pip) is a lysine catabolite involved in plant systemic acquired resistance (SAR). In this issue of Cell, Hartmann et al. (2018) demonstrate that a flavin-dependent monooxygenase converts Pip to N-hydroxypipecolic acid (NHP), which functions as a critical metabolic regulator of SAR in Arabidopsis.
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