Open AccessWeaving New Insights for the Genetic Regulation of Human Cognitive Phenotypes
Author(s) -
Bernard Mulvey,
Joseph D. Dougherty
Publication year - 2018
Publication title -
cell
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 26.304
H-Index - 776
eISSN - 1097-4172
pISSN - 0092-8674
DOI - 10.1016/j.cell.2017.12.037
Subject(s) - biology , weaving , phenotype , cognition , evolutionary biology , cognitive science , genetics , computational biology , gene , neuroscience , zoology , psychology
Psychiatric genetic studies have drawn associations between human cognitive traits and noncoding genomic variants. However, the mechanistic effects of these variants are unclear. By weaving in strands of genomic data from developing human brains, de la Torre-Ubieta et al. tie disease-associated loci to functional enhancers, target genes, and putatively affected cell types.
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