How the Gut Feels, Smells, and Talks | Zendy

Joep Beumer | Zendy; Hans Clevers | Zendy

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How the Gut Feels, Smells, and Talks

Author(s) -

Joep Beumer,

Hans Clevers

Publication year - 2017

Publication title -

cell

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 26.304

H-Index - 776

eISSN - 1097-4172

pISSN - 0092-8674

DOI - 10.1016/j.cell.2017.06.023

Subject(s) - enteroendocrine cell , biology , microbiology and biotechnology , gastrointestinal epithelium , homeostasis , intestinal epithelium , neuroscience , gastrointestinal tract , endocrine system , cell type , hormone , epithelium , serotonin , cell , endocrinology , receptor , genetics , biochemistry

Gut-brain signaling plays a central role in a range of homeostatic processes, yet details of this cross-talk remain enigmatic. In this issue of Cell, Bellono and colleagues identify a variety of luminal stimuli acting on serotonin-secreting enteroendocrine cells and, for the first time, demonstrate a functional synaptic interaction with neurons.

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