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Can We Just Say: Transcription Second?
Author(s) -
Peter H.L. Krijger,
Wouter de Laat
Publication year - 2017
Publication title -
cell
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 26.304
H-Index - 776
eISSN - 1097-4172
pISSN - 0092-8674
DOI - 10.1016/j.cell.2017.03.026
Subject(s) - biology , genome , maternal to zygotic transition , computational biology , genetics , transcription (linguistics) , function (biology) , drosophila melanogaster , transcription factor , evolutionary biology , zygote , gene , embryogenesis , linguistics , philosophy
The striking correlation between genome topology and transcriptional activity has for decades made researchers revisit the question, "Does form follow function, or does function follow form?" In a new study, Hug et al. address this question by comparing the timing of zygotic genome activation to the emergence of genome structures during Drosophila embryogenesis.

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