Next-Generation Sequencing of Circulating Tumor DNA for Early Cancer Detection
Author(s) -
Alexander M. Aravanis,
Mark Lee,
Richard D. Klausner
Publication year - 2017
Publication title -
cell
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 26.304
H-Index - 776
eISSN - 1097-4172
pISSN - 0092-8674
DOI - 10.1016/j.cell.2017.01.030
Subject(s) - biology , dna sequencing , cancer , nucleic acid , computational biology , cancer detection , dna , genetics
Curative therapies are most successful when cancer is diagnosed and treated at an early stage. We advocate that technological advances in next-generation sequencing of circulating, tumor-derived nucleic acids hold promise for addressing the challenge of developing safe and effective cancer screening tests.
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