Open AccessDisease Tolerance Trick or Treat: Give Your Brain Something Good to Eat
Author(s) -
Janelle S. Ayres
Publication year - 2016
Publication title -
cell
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 26.304
H-Index - 776
eISSN - 1097-4172
pISSN - 0092-8674
DOI - 10.1016/j.cell.2016.08.034
Subject(s) - biology , disease , anorexia , immunology , neuroscience , medicine
The reprioritization of feeding motivations during disease is proposed to optimize host defense strategies against infection. Now, Wang et al. identify that sickness-induced anorexia differentially shapes the metabolic requirements of cellular stress adaptations, leading to opposite impact on disease tolerance upon bacterial versus viral infections.
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