Open AccessBacterial Backstabbing: EF-Tu, Brute?
Author(s) -
Matthew T. Cabeen,
Richard Losick
Publication year - 2015
Publication title -
cell
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 26.304
H-Index - 776
eISSN - 1097-4172
pISSN - 0092-8674
DOI - 10.1016/j.cell.2015.10.007
Subject(s) - biology , offensive , warhead , secretion , microbiology and biotechnology , bacterial protein , toxin , microbial toxins , computational biology , genetics , bacteria , biochemistry , physics , management , nuclear physics , economics
Bacterial type VI secretion is an offensive and defensive weapon that utilizes a molecular warhead to inject toxins into neighboring cells. In this issue of Cell, Whitney et al. report a new class of toxin that disrupts the core metabolism of recipient cells and uncover a surprising requirement for EF-Tu.
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