Open AccessDaughter’s Tolerance of Mom Matters in Mate Choice
Author(s) -
Jeffrey R. Singer,
Casey T. Weaver
Publication year - 2015
Publication title -
cell
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 26.304
H-Index - 776
eISSN - 1097-4172
pISSN - 0092-8674
DOI - 10.1016/j.cell.2015.07.030
Subject(s) - offspring , biology , microchimerism , fetus , placenta , immune system , antigen , epigenome , immunology , genetics , mendelian inheritance , pregnancy , gene , dna methylation , gene expression
Mendelian genetics presumes inheritance of fitness through DNA. Kinder et al. find that maternal microchimerism induces stable immune tolerance to non-inherited maternal antigens in offspring. Female offspring that share these antigens with their mate experience reduced fetal wasting, establishing a role for vertical transmission of non-genetic information in reproductive fitness.
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