Open AccessThe Hunger Games
Author(s) -
Randy J. Seeley,
Kent Berridge
Publication year - 2015
Publication title -
cell
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 26.304
H-Index - 776
eISSN - 1097-4172
pISSN - 0092-8674
DOI - 10.1016/j.cell.2015.02.028
Subject(s) - biology , ghrelin , hypothalamus , leptin , food intake , neuroscience , food supply , feeding behavior , neuropeptide y receptor , endocrinology , medicine , microbiology and biotechnology , genetics , obesity , neuropeptide , hormone , receptor , agricultural science
Although AgRP and POMC neurons in the hypothalamus have long been associated with regulation of food intake, in this issue of Cell, Chen et al. use direct imaging in vivo to demonstrate rapid changes in their activity upon food presentation. The rapidity of their altered responses challenges classic notions of their functions and raises new hypotheses.
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