Open AccessMicrotubule Self-Organization via Protein-RNA Network Crosstalk
Author(s) -
C.H. Coles,
Frank Bradke
Publication year - 2014
Publication title -
cell
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 26.304
H-Index - 776
eISSN - 1097-4172
pISSN - 0092-8674
DOI - 10.1016/j.cell.2014.06.044
Subject(s) - biology , crosstalk , microtubule , microbiology and biotechnology , rna , rna processing , computational biology , genetics , gene , physics , optics
Microtubule plus-end tracking proteins are crucial for the regulation of microtubule dynamics. Preitner et al. report that one such protein, adenomatous polyposis coli (APC), also binds RNA and identify mRNAs encoding tubulin subunits within the brain APC-RNA interactome, suggesting a new mode of microtubule self-regulation.
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