Open AccessA New Twist on Transcriptional Bursting
Author(s) -
David Levens,
Daniel R. Larson
Publication year - 2014
Publication title -
cell
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 26.304
H-Index - 776
eISSN - 1097-4172
pISSN - 0092-8674
DOI - 10.1016/j.cell.2014.06.042
Subject(s) - biology , bursting , twist , computational biology , genetics , evolutionary biology , microbiology and biotechnology , neuroscience , mathematics , geometry
Transcriptional bursting has been observed across species and is one of the primary causes of variable gene expression in cells and tissue. In this issue, Chong et al. describe how DNA topology results in transcriptional bursting in E. coli.
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