The Shape of Things to Come | Zendy

Orkun Akin | Zendy; S Lawrence Zipursky | Zendy

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The Shape of Things to Come

Author(s) -

Orkun Akin,

S Lawrence Zipursky

Publication year - 2014

Publication title -

cell

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 26.304

H-Index - 776

eISSN - 1097-4172

pISSN - 0092-8674

DOI - 10.1016/j.cell.2013.12.037

Subject(s) - biology , cytoskeleton , microbiology and biotechnology , actin , motility , cytoplasm , regulator , morphogenesis , actin cytoskeleton , effector , receptor , cell , actin binding protein , actin remodeling , biochemistry , gene

Surface receptors can link binding of ligands to changes in the actin-based cell cytoskeleton. Chia et al. and Chen et al. provide evidence for direct binding between the cytoplasmic tails of receptors and the WAVE complex, a regulator of the actin nucleator Arp2/3 complex, which might help to explain how environmental signals are translated into changes in morphology and motility.

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