Open AccessCerebral Organoids in a Dish: Progress and Prospects
Author(s) -
Marina Bershteyn,
Arnold R. Kriegstein
Publication year - 2013
Publication title -
cell
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 26.304
H-Index - 776
eISSN - 1097-4172
pISSN - 0092-8674
DOI - 10.1016/j.cell.2013.09.010
Subject(s) - induced pluripotent stem cell , biology , organoid , embryonic stem cell , stem cell , neuroscience , microcephaly , microbiology and biotechnology , anatomy , genetics , gene
A three-dimensional culture of cortical tissues derived from pluripotent stem cells offers an opportunity to model human brain development and disorders. In a recent issue of Nature, Lancaster et al. describe a new method for generating cerebral organoids in a dish and use it to model microcephaly.
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