Open AccessInside-Out Connections: The ER Meets the Plasma Membrane
Author(s) -
Seth Malmersjö,
Tobias Meyer
Publication year - 2013
Publication title -
cell
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 26.304
H-Index - 776
eISSN - 1097-4172
pISSN - 0092-8674
DOI - 10.1016/j.cell.2013.05.054
Subject(s) - endoplasmic reticulum , biology , crosstalk , microbiology and biotechnology , membrane , stim1 , membrane contact site , plasma , membrane protein , integral membrane protein , biochemistry , physics , quantum mechanics , optics
Junctions that connect the endoplasmic reticulum (ER) and the plasma membrane (PM) are unique yet ubiquitous subcellular compartments. Giordano et al. now report that extended synaptotagmins (E-Syts) promote their formation, providing fundamental insight into the molecular machinery controlling ER and plasma membrane crosstalk.
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