This Message Will Self-Destruct: NMD Regulates Axon Guidance | Zendy

Nicolas Preitner | Zendy; Jie Quan | Zendy; John G. Flanagan | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Open Access

This Message Will Self-Destruct: NMD Regulates Axon Guidance

Author(s) -

Nicolas Preitner,

Jie Quan,

John G. Flanagan

Publication year - 2013

Publication title -

cell

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 26.304

H-Index - 776

eISSN - 1097-4172

pISSN - 0092-8674

DOI - 10.1016/j.cell.2013.05.019

Subject(s) - nonsense mediated decay , biology , translation (biology) , axon guidance , messenger rna , roundabout , microbiology and biotechnology , nonsense , growth cone , computational biology , axon , neuroscience , rna , genetics , gene , rna splicing

The navigation of axons to their final destination can involve a sequence of steps that require different sets of guidance receptors. In this issue, Colak et al. show that regulated intra-axonal protein synthesis coupled to nonsense-mediated mRNA decay (NMD) controls a switch in Robo3.2 expression that is critical for navigation.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research