z-logo
open-access-imgOpen Access
All Things to All People
Author(s) -
Trevor D. Littlewood,
Peter Kreuzaler,
Gérard I. Evan
Publication year - 2012
Publication title -
cell
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 26.304
H-Index - 776
eISSN - 1097-4172
pISSN - 0092-8674
DOI - 10.1016/j.cell.2012.09.006
Subject(s) - biology , leucine zipper , ectopic expression , gene , transcription factor , context (archaeology) , proto oncogene proteins c myc , microbiology and biotechnology , somatic cell , basic helix loop helix , genetics , transcription (linguistics) , dna binding protein , cancer research , paleontology , linguistics , philosophy
Myc is an enigma wrapped in a mystery. Attempts to identify Myc target genes, particularly in cancer, have been fraught with dead ends and context-specific functions. Lin et al. and Nie et al. address this conundrum by showing that Myc acts to amplify the output of existing transcriptionally active genes.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.
Having issues? You can contact us here
Accelerating Research

Address

John Eccles House
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom