Open AccessEgg's ZP3 Structure Speaks Volumes
Author(s) -
Paul M. Wassarman,
Eveline S. Litscher
Publication year - 2010
Publication title -
cell
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 26.304
H-Index - 776
eISSN - 1097-4172
pISSN - 0092-8674
DOI - 10.1016/j.cell.2010.10.013
Subject(s) - biology , zona pellucida , glycoprotein , zona pellucida glycoprotein , sperm , microbiology and biotechnology , extracellular , oocyte , genetics , embryo
Binding of mammalian sperm to eggs depends in part on ZP3, a glycoprotein in the egg's extracellular coat, the zona pellucida. In this issue, Han et al. (2010) describe the structure of an avian ZP3 homolog, providing insights into ZP3 processing and polymerization and the roles of the ZP3 polypeptide and its carbohydrate in sperm binding.
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