Induced Domain Formation in Endocytic Invagination, Lipid Sorting, and Scission | Zendy

Ludger Johannes | Zendy; Satyajit Mayor | Zendy

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Induced Domain Formation in Endocytic Invagination, Lipid Sorting, and Scission

Author(s) -

Ludger Johannes,

Satyajit Mayor

Publication year - 2010

Publication title -

cell

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 26.304

H-Index - 776

eISSN - 1097-4172

pISSN - 0092-8674

DOI - 10.1016/j.cell.2010.08.007

Subject(s) - biology , invagination , endocytic cycle , microbiology and biotechnology , domain (mathematical analysis) , anatomy , biochemistry , endocytosis , receptor , mathematics , mathematical analysis

Lipid segregation occurs in biological membranes, but how this plays into cellular processes like endocytosis has been unclear. Here, we discuss how the active or passive induction of lipid-protein domain formation in membranes can alter membrane mechanics and thus affect processes such as the generation of curvature, the scission of buds and tubules, and lipid sorting.

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