SnapShot: Lipid Droplets | Zendy

Natalie Krahmer | Zendy; Yi Guo | Zendy; Robert V. Farese | Zendy; Tobias C. Walther | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Open Access

SnapShot: Lipid Droplets

Author(s) -

Natalie Krahmer,

Yi Guo,

Robert V. Farese,

Tobias C. Walther

Publication year - 2009

Publication title -

cell

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 26.304

H-Index - 776

eISSN - 1097-4172

pISSN - 0092-8674

DOI - 10.1016/j.cell.2009.11.023

Subject(s) - biology , snapshot (computer storage) , lipid droplet , computational biology , microbiology and biotechnology , computer science , operating system

Lipid droplets (LDs) are universal cellular organelles that specialize in the storage of neutral lipids, such as sterol esters and triacylglycerols (see Essay by Farese and Walther, this issue). As such, they provide the main cellular reservoir for lipids of energy storage and membrane synthesis, and they protect cells from the lipotoxic effects of unesterified lipids. LDs also figure prominently in several diseases, including obesity, type 2 diabetes, liver steatosis, and atherosclerosis, which are characterized by the extensive accumulation of LDs in different cell types and tissues. Additionally, oils produced through the engineering of plant seeds and microorganisms (e.g., for production of biofuels) accumulate in LDs. LDs may also provide a cellular platform for specific proteins and processes. Intriguingly, several important intracellular pathogens, such as the hepatitis C virus and

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research