Open AccessSex on the Brain
Author(s) -
Khatuna Gagnidze,
Donald W. Pfaff
Publication year - 2009
Publication title -
cell
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 26.304
H-Index - 776
eISSN - 1097-4172
pISSN - 0092-8674
DOI - 10.1016/j.cell.2009.09.011
Subject(s) - biology , aromatase , testosterone (patch) , estrogen , sexual differentiation , endocrinology , medicine , neuroscience , genetics , gene , cancer , breast cancer
Release of testosterone during early development is necessary for masculinization of brain structures in rodents. Wu et al. (2009) now elucidate the neuronal changes caused by aromatase-mediated conversion of testosterone into estrogen in perinatal mice and the ensuing effects on adult behavior.
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