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Learning Tolerance while Fighting Ignorance
Author(s) -
Philippe Sansonetti,
Ruslan Medzhitov
Publication year - 2009
Publication title -
cell
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 26.304
H-Index - 776
eISSN - 1097-4172
pISSN - 0092-8674
DOI - 10.1016/j.cell.2009.07.024
Subject(s) - biology , host (biology) , ignorance , immune system , commensalism , gut bacteria , bacteria , gut flora , microbiology and biotechnology , immunology , ecology , genetics , philosophy , epistemology
Research on microbe-host interactions focuses principally on pathogens, yet our immune system must deal with the huge number of beneficial commensal bacteria in our gut. It is becoming clear that the host immune system must reach a delicate balance between destroying dangerous bacterial pathogens while preserving the beneficial gut microbiota.

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