Open AccessClosing in on Mechanisms of Tissue Morphogenesis
Author(s) -
Matteo Rauzi,
Thomas Lecuit
Publication year - 2009
Publication title -
cell
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 26.304
H-Index - 776
eISSN - 1097-4172
pISSN - 0092-8674
DOI - 10.1016/j.cell.2009.06.009
Subject(s) - biology , morphogenesis , closing (real estate) , evolutionary biology , microbiology and biotechnology , computational biology , genetics , gene , political science , law
It remains largely unknown how large-scale tissue movements during development emerge from the interplay of different tensile forces associated with actomyosin networks. Solon et al. (2009) now report that a ratchet-like mechanism drives the movement of epithelial sheets during dorsal closure in embryos of the fruit fly Drosophila.
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