Open AccessFOXP2 and Human Cognition
Author(s) -
Philip Lieberman
Publication year - 2009
Publication title -
cell
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 26.304
H-Index - 776
eISSN - 1097-4172
pISSN - 0092-8674
DOI - 10.1016/j.cell.2009.05.013
Subject(s) - foxp2 , biology , basal ganglia , neuroscience , cognition , human brain , synaptic plasticity , neuroplasticity , cognitive science , central nervous system , gene , genetics , psychology , transcription factor , receptor
Using a mouse model, Enard et al. (2009) show that the human form of the FOXP2 gene increases synaptic plasticity and dendrite connectivity in the basal ganglia. These results partly explain the enhanced capability of cortico-basal ganglia circuits in the human brain that regulate critical aspects of language, cognition, and motor control.
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