Open AccessOpening Windows to the Genome
Author(s) -
Iestyn Whitehouse,
Toshio Tsukiyama
Publication year - 2009
Publication title -
cell
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 26.304
H-Index - 776
eISSN - 1097-4172
pISSN - 0092-8674
DOI - 10.1016/j.cell.2009.04.026
Subject(s) - biology , saccharomyces cerevisiae , nucleosome , chromatin , promoter , budding yeast , genetics , genome , yeast , regulator , gene , computational biology , microbiology and biotechnology , gene expression
Recent mapping of nucleosome positioning has added a new dimension to the study of transcriptional regulation. Hartley and Madhani (2009) now demonstrate the power of this approach and show that a chromatin regulator alters nucleosome positioning in the promoters of a large number of genes in the budding yeast Saccharomyces cerevisiae.
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