Open AccessIn DNA Replication, the Early Bird Catches the Worm
Author(s) -
Erik Boye,
Beáta Grallert
Publication year - 2009
Publication title -
cell
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 26.304
H-Index - 776
eISSN - 1097-4172
pISSN - 0092-8674
DOI - 10.1016/j.cell.2009.02.023
Subject(s) - biology , dna replication , replication (statistics) , dna , genetics , zoology , evolutionary biology , virology
The initiation of DNA replication is a complex, multistep process with important implications for genomic stability. In this issue, Wu and Nurse (2009) find that initiation factors are differentially recruited to replication origins. They uncover evidence suggesting that the efficiency of this recruitment may determine whether and when an origin is used to initiate DNA replication in S phase.
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