mRNA Localization: Gene Expression in the Spatial Dimension | Zendy

Kelsey C. Martin | Zendy; Anne Ephrussi | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Open Access

mRNA Localization: Gene Expression in the Spatial Dimension

Author(s) -

Kelsey C. Martin,

Anne Ephrussi

Publication year - 2009

Publication title -

cell

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 26.304

H-Index - 776

eISSN - 1097-4172

pISSN - 0092-8674

DOI - 10.1016/j.cell.2009.01.044

Subject(s) - biology , microbiology and biotechnology , rna , cytoplasm , gene expression , subcellular localization , cytoskeleton , gene , rna binding protein , messenger rna , regulation of gene expression , genetics , cell

The localization of mRNAs to subcellular compartments provides a mechanism for regulating gene expression with exquisite temporal and spatial control. Recent studies suggest that a large fraction of mRNAs localize to distinct cytoplasmic domains. In this Review, we focus on cis-acting RNA localization elements, RNA-binding proteins, and the assembly of mRNAs into granules that are transported by molecular motors along cytoskeletal elements to their final destination in the cell.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research