Open AccessElongator Bridges Tubulin Acetylation and Neuronal Migration
Author(s) -
Anthony WynshawBoris
Publication year - 2009
Publication title -
cell
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 26.304
H-Index - 776
eISSN - 1097-4172
pISSN - 0092-8674
DOI - 10.1016/j.cell.2009.01.024
Subject(s) - biology , acetylation , acetyltransferase , histone acetyltransferase , neuronal migration , microbiology and biotechnology , tubulin , cerebral cortex , histone , neuroscience , cortex (anatomy) , cell migration , microtubule , cell , genetics , gene
Neuronal cell migration and maturation are crucial for the development of the mammalian cerebral cortex. In this issue, Creppe et al. (2009) now show that the multisubunit histone acetyltransferase Elongator may regulate migration and branch formation of cortical neurons in the developing mouse brain by acetylating alpha-tubulin.
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