Understanding the Words of Chromatin Regulation
Author(s) -
Jiang Wu,
Julie Lessard,
Robert H. Crabtree
Publication year - 2009
Publication title -
cell
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 26.304
H-Index - 776
eISSN - 1097-4172
pISSN - 0092-8674
DOI - 10.1016/j.cell.2009.01.009
Subject(s) - chromatin , biology , histone , computational biology , chia pet , histone modifying enzymes , histone code , genetics , microbiology and biotechnology , chromatin remodeling , nucleosome , dna
Recent studies indicate that chromatin regulatory complexes produce biological specificity in the way that letters produce meanings by combinations into words. Combinatorial assembly of chromatin regulatory complexes may be critical for maximizing the information content provided by arrays of histone modifications.
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