Open Accessp38δ and PKD1: Kinase Switches for Insulin Secretion
Author(s) -
Ana Cuenda,
Ángel R. Nebreda
Publication year - 2009
Publication title -
cell
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 26.304
H-Index - 776
eISSN - 1097-4172
pISSN - 0092-8674
DOI - 10.1016/j.cell.2009.01.005
Subject(s) - biology , secretion , microbiology and biotechnology , pkd1 , insulin , p38 mitogen activated protein kinases , kinase , protein kinase a , genetics , endocrinology , polycystic kidney disease , kidney
Insufficient production of the hormone insulin by pancreatic beta cells results in diabetes. In this issue, Sumara et al. (2009) report key roles for the protein kinases p38delta and PKD1 in the regulation of insulin secretion as well as in the survival of pancreatic beta cells.
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