Open AccessAutophagy SEPArates Germline and Somatic Cells
Author(s) -
Eric H. Baehrecke
Publication year - 2009
Publication title -
cell
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 26.304
H-Index - 776
eISSN - 1097-4172
pISSN - 0092-8674
DOI - 10.1016/j.cell.2009.01.003
Subject(s) - biology , germline , somatic cell , autophagy , microbiology and biotechnology , genetics , gene , apoptosis
Cellular determinants of the germline selectively accumulate in germ cell precursors and influence cell fate during early development in many organisms. Zhang et al. (2009) now report that targeted autophagy mediated by the SEPA-1 protein depletes germplasm proteins from somatic cells during early development of the nematode.
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