Who Benefits from Granulomas, Mycobacteria or Host?
Author(s) -
Tyler D. Bold,
J. Ernst
Publication year - 2009
Publication title -
cell
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 26.304
H-Index - 776
eISSN - 1097-4172
pISSN - 0092-8674
DOI - 10.1016/j.cell.2008.12.032
Subject(s) - biology , host (biology) , microbiology and biotechnology , tuberculosis , mycobacterium , granuloma , host response , immunology , bacteria , ecology , genetics , pathology , immune system , medicine
By investigating host-pathogen interactions in zebrafish using intravital imaging, Davis and Ramakrishnan (2009) provide evidence that aggregates of immune cells known as granulomas, long thought to constrain mycobacterial infection, may instead facilitate its spread.
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