Intraoperative changes in the H-reflex pathway during deep brain stimulation surgery for Parkinson’s disease: A potential biomarker for optimal electrode placement | Zendy

Jennifer C. Andrews | Zendy; François D. Roy | Zendy; Fang Ba | Zendy; Tejas Sankar | Zendy

Open Access

Intraoperative changes in the H-reflex pathway during deep brain stimulation surgery for Parkinson’s disease: A potential biomarker for optimal electrode placement

Author(s) -

Jennifer C. Andrews,

François D. Roy,

Fang Ba,

Tejas Sankar

Publication year - 2020

Publication title -

brain stimulation

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.685

H-Index - 81

eISSN - 1935-861X

pISSN - 1876-4754

DOI - 10.1016/j.brs.2020.09.024

Subject(s) - deep brain stimulation , parkinson's disease , medicine , stimulation , biomarker , reflex , disease , neuroscience , surgery , anesthesia , physical medicine and rehabilitation , psychology , pathology , biology , biochemistry

Deep Brain Stimulation (DBS) targeting the subthalamic nucleus (STN) and globus pallidus interna (GPi) is an effective treatment for cardinal motor symptoms and motor complications in Parkinson's Disease (PD). However, malpositioned DBS electrodes can result in suboptimal therapeutic response.

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