Gait-related frequency modulation of beta oscillatory activity in the subthalamic nucleus of parkinsonian patients
Author(s) -
Andrea Canessa,
Chiara Palmisano,
Ioannis U. Isaias,
Alberto Mazzoni
Publication year - 2020
Publication title -
brain stimulation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.685
H-Index - 81
eISSN - 1935-861X
pISSN - 1876-4754
DOI - 10.1016/j.brs.2020.09.006
Subject(s) - subthalamic nucleus , physical medicine and rehabilitation , gait , beta (programming language) , modulation (music) , neuroscience , medicine , psychology , physics , parkinson's disease , deep brain stimulation , computer science , disease , acoustics , programming language
Abnormal beta band activity in the subthalamic nucleus (STN) is known to be exaggerated in patients with Parkinson's disease, and the amplitude of such activity has been associated with akinetic rigid symptoms. New devices for deep brain stimulation (DBS) that operate by adapting the stimulation parameters generally rely on the detection of beta activity amplitude modulations in these patients. Movement-related frequency modulation of beta oscillatory activity has been poorly investigated, despite being an attractive variable for extracting information about basal ganglia activity.
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