Age-related differences of motor cortex plasticity in adults: A transcranial direct current stimulation study | Zendy

Ensiyeh Ghasemian-Shirvan | Zendy; Leila Farnad | Zendy; Mohsen Mosayebi-Samani | Zendy; Stefanie Verstraelen | Zendy; Raf Meesen | Zendy; MinFang Kuo | Zendy; Michael A. Nitsche | Zendy

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Age-related differences of motor cortex plasticity in adults: A transcranial direct current stimulation study

Author(s) -

Ensiyeh Ghasemian-Shirvan,

Leila Farnad,

Mohsen Mosayebi-Samani,

Stefanie Verstraelen,

Raf Meesen,

MinFang Kuo,

Michael A. Nitsche

Publication year - 2020

Publication title -

brain stimulation

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.685

H-Index - 81

eISSN - 1935-861X

pISSN - 1876-4754

DOI - 10.1016/j.brs.2020.09.004

Subject(s) - transcranial direct current stimulation , neuroplasticity , transcranial magnetic stimulation , motor cortex , neuroscience , stimulation , psychology , plasticity , long term potentiation , brain stimulation , primary motor cortex , medicine , physics , receptor , thermodynamics

Cognitive, and motor performance are reduced in aging, especially with respect to acquisition of new knowledge, which is associated with a neural plasticity decline. Animal models show a reduction of long-term potentiation, but not long-term depression, in higher age. Findings in humans are more heterogeneous, with some studies showing respective deficits, but others not, or mixed results, for plasticity induced by non-invasive brain stimulation. One reason for these heterogeneous results might be the inclusion of different age ranges in these studies. In addition, a systematic detailed comparison of the age-dependency of neural plasticity in humans is lacking so far.

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