Distinct perceptive pathways selected with tonic and bursting patterns of thalamic stimulation | Zendy

Matthew S. Willsey | Zendy; Charles W. Lu | Zendy; Sam R. Nason | Zendy; Karlo A. Malaga | Zendy; Scott F. Lempka | Zendy; Cynthia A. Chestek | Zendy; Parag G. Patil | Zendy

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Distinct perceptive pathways selected with tonic and bursting patterns of thalamic stimulation

Author(s) -

Matthew S. Willsey,

Charles W. Lu,

Sam R. Nason,

Karlo A. Malaga,

Scott F. Lempka,

Cynthia A. Chestek,

Parag G. Patil

Publication year - 2020

Publication title -

brain stimulation

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.685

H-Index - 81

eISSN - 1935-861X

pISSN - 1876-4754

DOI - 10.1016/j.brs.2020.07.007

Subject(s) - bursting , tonic (physiology) , neuroscience , stimulation , psychology

Novel patterns of electrical stimulation of the brain and spinal cord hold tremendous promise to improve neuromodulation therapies for diverse disorders, including tremor and pain. To date, there are limited numbers of experimental studies in human subjects to help explain how stimulation patterns impact the clinical response, especially with deep brain stimulation. We propose using novel stimulation patterns during electrical stimulation of somatosensory thalamus in awake deep brain stimulation surgeries and hypothesize that stimulation patterns will influence the sensory percept without moving the electrode.

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