Decreased interhemispheric connectivity and increased cortical excitability in unmedicated schizophrenia: A prefrontal interleaved TMS fMRI study
Author(s) -
Ryan Webler,
Carmen Hamady,
Chris Molnar,
Kevin A. Johnson,
Leo Bonilha,
Berry Anderson,
Claartje Bruin,
Daryl E. Bohning,
Mark S. George,
Ziad Nahas
Publication year - 2020
Publication title -
brain stimulation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.685
H-Index - 81
eISSN - 1935-861X
pISSN - 1876-4754
DOI - 10.1016/j.brs.2020.06.017
Subject(s) - neuroscience , schizophrenia (object oriented programming) , psychology , functional connectivity , prefrontal cortex , psychiatry , cognition
Prefrontal abnormalities in schizophrenia have consistently emerged from resting state and cognitive neuroimaging studies. However, these correlative findings require causal verification via combined imaging/stimulation approaches. To date, no interleaved transcranial magnetic stimulation and functional magnetic resonance imaging study (TMS fMRI) has probed putative prefrontal cortex abnormalities in schizophrenia.
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