Transcranial direct current stimulation combined with exercise modulates the inflammatory profile and hyperalgesic response in rats subjected to a neuropathic pain model: Long-term effects | Zendy

Bettega Costa Lopes | Zendy; Liciane Fernandes Medeiros | Zendy; Vanessa Silva de Souza | Zendy; Stefania Giotti Cioato | Zendy; Helouise Richardt Medeiros | Zendy; Gabriela Gregory Regner | Zendy; Camila Lino de Oliveira | Zendy; Felipe Fregni | Zendy; Wolnei Caumo | Zendy; Iraci Lucena da Silva Torres | Zendy

Open Access

Transcranial direct current stimulation combined with exercise modulates the inflammatory profile and hyperalgesic response in rats subjected to a neuropathic pain model: Long-term effects

Author(s) -

Bettega Costa Lopes,

Liciane Fernandes Medeiros,

Vanessa Silva de Souza,

Stefania Giotti Cioato,

Helouise Richardt Medeiros,

Gabriela Gregory Regner,

Camila Lino de Oliveira,

Felipe Fregni,

Wolnei Caumo,

Iraci Lucena da Silva Torres

Publication year - 2020

Publication title -

brain stimulation

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.685

H-Index - 81

eISSN - 1935-861X

pISSN - 1876-4754

DOI - 10.1016/j.brs.2020.02.025

Subject(s) - neuropathic pain , medicine , nociception , brainstem , hyperalgesia , anesthesia , transcranial direct current stimulation , spinal cord , sciatic nerve , chronic pain , aerobic exercise , neuromodulation , central nervous system , stimulation , physical therapy , receptor , psychiatry

Behavioral alterations, like mechanical and thermal hyperalgesia, and modulation of biomarkers in the peripheral and central nervous systems (CNS) are markers of chronic pain. Transcranial direct current stimulation (tDCS) with exercise is a promising therapy for pain due to its neuromodulatory capacity.

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