Matching stimulation paradigms resolve apparent differences between optogenetic and electrical VTA stimulation | Zendy

Theresa Weidner | Zendy; Daniel Vincenz | Zendy; Marta Brocka | Zendy; Jennifer Tegtmeier | Zendy; Anja M. Oelschlegel | Zendy; Frank W. Ohl | Zendy; Jürgen Goldschmidt | Zendy; M. Lippert | Zendy

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Matching stimulation paradigms resolve apparent differences between optogenetic and electrical VTA stimulation

Author(s) -

Theresa Weidner,

Daniel Vincenz,

Marta Brocka,

Jennifer Tegtmeier,

Anja M. Oelschlegel,

Frank W. Ohl,

Jürgen Goldschmidt,

M. Lippert

Publication year - 2019

Publication title -

brain stimulation

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.685

H-Index - 81

eISSN - 1935-861X

pISSN - 1876-4754

DOI - 10.1016/j.brs.2019.11.005

Subject(s) - optogenetics , stimulation , neuroscience , deep brain stimulation , matching (statistics) , medicine , psychology , disease , parkinson's disease , pathology

Optogenetic stimulation has grown into a popular brain stimulation method in basic neuroscience while electrical stimulation predominates in clinical applications. In order to explain the effects of electrical stimulation on a cellular level and evaluate potential advantages of optogenetic therapies, comparisons between the two stimulation modalities are necessary. This comparison is hindered, however, by the difficulty of effectively matching the two fundamentally different modalities.

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