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Brain oscillation-synchronized stimulation of the left dorsolateral prefrontal cortex in depression using real-time EEG-triggered TMS
Author(s) -
Brigitte Zrenner,
Christoph Zrenner,
Pedro Caldana Gordon,
Paolo Belardinelli,
Eric James McDermott,
Surjo R. Soekadar,
Andreas J. Fallgatter,
Ulf Ziemann,
Florian MüllerDahlhaus
Publication year - 2019
Publication title -
brain stimulation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.685
H-Index - 81
eISSN - 1935-861X
pISSN - 1876-4754
DOI - 10.1016/j.brs.2019.10.007
Subject(s) - electroencephalography , dorsolateral prefrontal cortex , transcranial magnetic stimulation , neuroscience , dorsolateral , depression (economics) , psychology , stimulation , brain stimulation , oscillation (cell signaling) , prefrontal cortex , medicine , cognition , biology , genetics , economics , macroeconomics
Repetitive transcranial magnetic stimulation (rTMS) of the left dorsolateral prefrontal cortex (DLPFC) is an effective treatment for major depressive disorder (MDD), but response rates are low and effect sizes small. Synchronizing TMS pulses with instantaneous brain oscillations can reduce variability and increase efficacy of TMS-induced plasticity.

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