Beta-Adrenergic Receptor Genes Are Associated With Arterial Stiffness in Black and White Adults: The Bogalusa Heart Study | Zendy

W CHEN | Zendy; S SRINIVASAN | Zendy; E BOERWINKLE | Zendy; G BERENSON | Zendy

Open Access

Beta-Adrenergic Receptor Genes Are Associated With Arterial Stiffness in Black and White Adults: The Bogalusa Heart Study

Author(s) -

W CHEN,

S SRINIVASAN,

E BOERWINKLE,

G BERENSON

Publication year - 2007

Publication title -

american journal of hypertension

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.009

H-Index - 136

eISSN - 1941-7225

pISSN - 0895-7061

DOI - 10.1016/j.amjhyper.2007.09.002

Subject(s) - arterial stiffness , medicine , adrenergic receptor , endocrinology , sympathetic nervous system , receptor , β2 adrenergic receptor , adrenergic , cardiology , blood pressure , agonist

Sympathetic nervous activity, which is regulated by the beta-adrenergic receptor (beta-AR), is an important determinant of the arterial wall-stiffening process. This study examines the genetic influence of beta-AR gene polymorphisms (beta(1)-AR Arg389Gly, beta(2)-AR Arg16Gly, and beta(3)-AR Trp64Arg) on arterial stiffness in black and white young adults.

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