G-6A Polymorphism of Angiotensinogen Gene Modulates the Effect of Blood Pressure on Carotid Intima-Media ThicknessThe Bogalusa Heart Study
Author(s) -
Azad R. Bhuiyan,
Wei Chen,
S SRINIVASAN,
J RICE,
Nancy B. Mock,
R TANG,
M BOND,
E BOERWINKLE,
G BERENSON
Publication year - 2007
Publication title -
american journal of hypertension
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.009
H-Index - 136
eISSN - 1941-7225
pISSN - 0895-7061
DOI - 10.1016/j.amjhyper.2007.06.001
Subject(s) - medicine , blood pressure , intima media thickness , body mass index , endocrinology , cardiology , common carotid artery , insulin resistance , allele , obesity , carotid arteries , biology , genetics , gene
The adverse association between blood pressure and carotid artery intima-media thickness (IMT), a surrogate measure of subclinical atherosclerosis, is well-known. However, whether the G-6A polymorphism of the angiotensinogen (AGT) gene, a candidate gene of hypertension and vascular remodeling, modulates this relationship is unknown.
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